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Thermo Scientific™ GeneBLAzer™ D1-CRE-bla CHO-K1 Cells

Catalog No. K1709
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Description

GeneBLAzer™ D1-CRE-bla CHO-K1 cells contain the human Dopamine Receptor 1 (D1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.

GeneBLAzer™ D1-CRE-bla CHO-K1 cells contain the human Dopamine Receptor 1 (D1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. No. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ D1-CRE-bla CHO-K1cells are functionally validated for Z' and EC50 concentrations of dihydrexidine. In addition, GeneBLAzer™ D1-CRE-bla CHO-K1 DA cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

Agonists and antagonists of dopamine D1 receptors are in various stages of clinical trials for the treatment of neurological disorders like Parkinson's disease, Alzheimer's disease, schizophrenia, and psychosis.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

TRUSTED_SUSTAINABILITY

Specifications

Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• GeneBLAzer™ D1-CRE-bla CHO-K1 cells
• GeneBLAzer™ D1-CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ D1-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method Fluorescence
For Use With (Application) FRET
Gene Symbol DRD1
Product Line GeneBLAzer
Quantity 2 x 106 Cells
Reporter Gene BLA (Beta-Lactamase)
Target Entry DRD1, D1
Type CHO-K1 Cells
Cell Line CHO-K1
System Type GeneBLAzer™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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