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Thermo Scientific™ GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 Cells

Catalog No. K1717
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K1717 2 x 106 Cells
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Catalog No. K1717 Supplier Thermo Scientific™ Supplier No. K1717
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Description

GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 6 (P2RY6) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.

GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 6 (P2RY6) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of UDP. In addition, GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

P2RY6 has been found in a variety of rat tissue such as; placenta, spleen, thymus, lung, stomach, intestine, mesentery, heart, and aorta. P2RY6 is activated by UDP, which functions as a full agonist. P2RY6 is activated either weakly or not at all by additional extracellular nucleotides such as UTP, ATP, and ADP. P2RY6 has been implicated to be involved in ion transport, vasodilatation, and contraction of smooth muscle.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_004154.3
Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol/

Includes:
• GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells
• GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ P2RY6-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method Fluorescence
For Use With (Application) FRET
Gene Symbol P2RY6
Population Status Single Cell Clone Origin
Product Line GeneBLAzer
Quantity 2 x 106 Cells
Reporter Gene BLA (Beta-Lactamase)
Target Entry P2RY6
Cell Line CHO-K1
System Type GeneBLAzer™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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