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Thermo Scientific™ GeneBLAzer™ VPAC2-CRE-bla CHO-K1 Cells

Catalog No. K1706
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2 x 106 Cells
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K1706 2 x 106 Cells
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Catalog No. K1706 Supplier Thermo Scientific™ Supplier No. K1706
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Description

GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells contain the human Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 2 (VPAC2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.

CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of VIP. In addition, GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

VPAC2 has been implicated in a wide range of autoimmune and inflammation disorders, including Chronic obstructive pulmonary disease, Chronic Fatigue Syndrome. VPAC2 may also play a role in Type-2 diabetes.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_003382.3
Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage Contents:
K1706 GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells
• GeneBLAzer™ VPAC2-CRE-bla CHO-K1 Assay Protocol
• Certificate of Analysis

Storage:
The GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method Fluorescence
For Use With (Application) FRET
Gene Symbol VPAC2
Population Status Single Cell Clone Origin
Product Line GeneBLAzer
Quantity 2 x 106 Cells
Reporter Gene BLA (Beta-Lactamase)
Target Entry VPAC2
Cell Line CHO-K1
System Type GeneBLAzer™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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