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GFI1 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody
$156.65 - $620.58
Specifications
Antigen | GFI1 |
---|---|
Concentration | Lot-Specific |
Applications | Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3491
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Active Motif
61554 |
10 μL |
Each for $156.65
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50-199-3490
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Active Motif
61553 |
100 μL |
Each for $620.58
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Description
GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.Specifications
GFI1 | |
Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
Q99684 | |
2672 | |
This antibody was raised against a peptide within the N-terminal region of human GFI1. | |
Primary | |
-20°C, Avoid Freeze/Thaw Cycles | |
GFI1 |
Lot-Specific | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5 | |
AW495828; FLJ94509; GFI1; Gfi-1; GFI1A; growth factor independence-1; growth factor independent 1; growth factor independent 1 transcription repressor; growth factor independent 1 transcriptional repressor; Growth factor independent protein 1; Growth factor independent-1; Pal1; Pal-1; SCN2; Zinc finger protein 163; Zinc finger protein Gfi-1; ZNF163 | |
GFI1 | |
IgG | |
Antigen affinity chromatography | |
Antibody |
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