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Glypican 3 Antibody (SPM595), Alexa Fluor™ 350, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP247761AF350
Description
Glypican 3 Monoclonal specifically detects Glypican 3 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.Specifications
Glypican 3 | |
Monoclonal | |
Alexa Fluor 350 | |
50mM Sodium Borate with 0.05% Sodium Azide | |
GPC3 | |
A recombinant fragment containing amino acids 511-580 of human Glypican 3 (Uniprot: P51654) | |
0.1 mL | |
Primary | |
Human | |
IgG1 κ |
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence | |
SPM595 | |
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence | |
DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS | |
Mouse | |
Protein A or G purified | |
RUO | |
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma. | |
Store at 4°C in the dark. |
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