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GM-CSF Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501731773 Shop All Proteintech Group Inc Products
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50-173-1773 150 μL
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Catalog No. 50-173-1773 Supplier Proteintech Group Inc Supplier No. 177621AP150UL
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Description

Rabbit Polyclonal Antibody

GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombit GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).

Specifications

Antigen GM-CSF
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CSF2
Gene Accession No. P01587, P04141
Gene Alias Colony stimulating factor, CSF, CSF2, GM CSF, GMCSF, Molgramostin, Sargramostim
Gene Symbols CSF2
Host Species Rabbit
Immunogen GM-CSF Fusion Protein Ag12142
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12981, 1437
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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