Invitrogen™ GNS Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5110785	Invitrogen™ PA5110785	100 μL
PIPA5111276	Invitrogen™ PA5111276	100 μL

Description

Immunogen sequence: DVLVEYQGEG RNVTDPTCPS LSPGVSQCFP DCVCEDAYNN TYACVRTMSA LWNLQYCEFD DQEVFVEVYN LTADPDQITN IAKTIDPELL GKMNYRLMML QSCSGPTCRT PGVFDPGYRF DPRLMFSNRG SVRTRRF.

GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

Specifications

• Antigen: GNS
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: GNS
• Gene Alias: 2610016K11Rik; AU042285; C87209; G6S; glucosamine (N-acetyl)-6-sulfatase; glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID); glucosamine -6-sulfatase; glucosamine-6-sulfatase; Gns; N28088; N-acetylglucosamine 6-sulfatase precursor; N-acetylglucosamine-6-sulfatase
• Gene Symbols: GNS
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography

• Concentration: 0.05 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P15586
• Gene ID (Entrez): 2799
• Immunogen: Recombinant Protein corresonding to Human GNS. Recombinant protein control fragment (Product #RP-90257).
• Product Type: Antibody