Tocris Golgicide A
Potent, specific and reversible inhibitor of GBF1 ArfGEF
Manufacturer: Tocris 3584/50
DescriptionPotent, specific and reversible inhibitor of Golgi BFA resistance factor 1 (GBF1), an ArfGEF, that decreases Arf1 activation in vivo. Arrests secretion of soluble and membrane-associated proteins at the endoplasmic reticulum-Golgi intermediate compartment. Causes disassembly and dispersal of the Golgi and trans-Golgi network.
- Chemical Name: 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
- Formula: C17H14F2N2
- CAS Number: 1139889-93-2
- Solubility: Soluble to 50mM in DMSO
- Purity: >98
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