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gp96/HSP90B1/GRP94 Antibody (9G10.F8.2) - IHC-Prediluted, Novus Biologicals™
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Catalog No. NBP248046 Shop All R&D Systems Products
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NBP248046 7 mL
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Catalog No. NBP248046 Supplier Novus Biologicals Supplier No. NBP248046
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Description

Rat Monoclonal Antibody

gp96/HSP90B1/GRP94 Monoclonal specifically detects gp96/HSP90B1/GRP94 in Human, Mouse, Rat, Porcine, Bovine, Canine, Chicken, Equine, Guinea Pig, Hamster, Monkey, Rabbit, Sheep, Xenopus samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen gp96/HSP90B1/GRP94
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 9G10.F8.2
Conjugate Unconjugated
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias 94 kDa glucose-regulated protein, endothelial cell (HBMEC) glycoprotein, glucose regulated protein, 94 kDa, GP96ECGP, GRP-94, GRP94gp96 homolog, Heat shock protein 90 kDa beta member 1, heat shock protein 90kDa beta (Grp94), member 1, TRA1endoplasmin, tumor rejection antigen (gp96) 1, Tumor rejection antigen 1, Tumor rejection antigen-1 (gp96)
Gene Symbols HSP90B1
Host Species Rat
Immunogen Purified glucose regulated protein 94 (grp94) from chicken oviducts (Uniprot: P14625)
Molecular Weight of Antigen 94 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Cancer, Cellular Markers, ER Markers, Golgi Apparatus Markers, Hypoxia, Membrane Trafficking and Chaperones
Primary or Secondary Primary
Gene ID (Entrez) 7184
Test Specificity Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This monoclonal antibody is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Target Species Human, Mouse, Rat, Pig, Canine, Chicken, Equine, Guinea Pig, Hamster, Primate, Monkey, Rabbit, Sheep, Xenopus species
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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