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Invitrogen™ GRB2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5111002
Description
Immunogen sequence: YVQALFDFDP QEDGELGFRR GDFIHVMDNS DPNWWKGACH GQTGMFPRNY VTPVNRNV.
GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
Specifications
GRB2 | |
Polyclonal | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P62993 | |
GRB2 | |
Recombinant Protein corresonding to Human GRB2. Recombinant protein control fragment (Product #RP-104615). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Western Blot, Immunocytochemistry | |
Unconjugated | |
GRB2 | |
AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
2885 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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