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GRB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501726154 Shop All Proteintech Group Inc Products
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50-172-6154 150 μL
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Catalog No. 50-172-6154 Supplier Proteintech Group Inc Supplier No. 102542AP150UL
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Description

Rabbit Polyclonal Antibody

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2 - Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.

Specifications

Antigen GRB2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene GRB2
Gene Accession No. P62993, P62994, Q60631
Gene Alias Adapter protein GRB2, ASH, EGFRBP GRB2, GRB2, Grb3 3, MST084, MSTP084, Protein Ash, SH2/SH3 adapter GRB2
Gene Symbols GRB2
Host Species Rabbit
Immunogen GRB2 Fusion Protein Ag0395
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14784, 2885, 81504
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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