Tocris™ GSK 650394

Serum- and glucocorticoid-regulated kinase (SGK) inhibitor

Manufacturer: Tocris™ 3572/50

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Catalog No. 35-725-0R

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Disclaimers:

For Research Use Only


    Specifications

    Product Type GSK 650394
    Inhibitors GSK 650394
    Purity >97
    Molecular Weight 382.45
    Quantity 50mg

    Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor (IC50 values are 62 and 103nM for SGK1 and SGK2 respectively). Displays >30-fold selectivity over Akt and other related kinases. Inhibits androgen-stimulated growth of LNCaP cells, a human prostate carcinoma cell line (IC50 ~ 1µM).

    • Chemical Name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoic acid
    • Formula: C25H22N2O2
    • CAS Number: 890842-28-1
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >97

  • Description & Specifications

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