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Tocris Bioscience™ GSK J1

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Quantity:
10 mg
50 mg
Description
Potent inhibitor of the H3K27 histone demethylases JMJD3 (KDM6B) and UTX (KDM6A) (IC50 values are 28 and 53 nM respectively). Also inhibits KDM5B, KDM5C and KDM5A (IC50 values are 170, 550 and 6,800 nM respectively). Exhibits no activity against a panel of other histone demethylases (IC50 >20 μM), and displays no significant inhibitory activity against 100 protein kinases at a concentration of 30 μM.
Ethyl ester derivative and Negative Control also available.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 389.45 |
Purity | >99% |
Molecular Weight (g/mol) | 389.459 |
Chemical Name or Material | GSK J1 |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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