GSK2578215A, Tocris Bioscience
Potent, selective LRRK2 inhibitor; brain penetrant
Manufacturer: Tocris Bioscience 4629/25
DescriptionPotent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant.
|Observed MW: 399.42|
Safety and Handling
Recommended Storage : Store at Room Temperature
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