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GSK2578215A
Potent, selective LRRK2 inhibitor; brain penetrant
$198.36 - $747.04
Specifications
| Chemical Name or Material | 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide |
|---|---|
| CAS | 1285515-21-0 |
| Assay Percent Range | >99% |
| Molecular Formula | C24H18FN3O2 |
| Formula Weight | Observed MW: 399.42 |
Description
Potent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylation in vitro and in peripheral tissues in vivo. Brain penetrant.Specifications
| 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide | |
| >99% | |
| Observed MW: 399.42 |
| 1285515-21-0 | |
| C24H18FN3O2 |
Safety and Handling
Recommended Storage : Store at Room Temperature
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