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  8. GW 0742, Tocris Bioscience™

GW 0742, Tocris Bioscience™

Catalog Number 222910
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
317318-84-6
C21H17F4NO3S2
471.485
HWVNEWGKWRGSRK-UHFFFAOYSA-N
chembl38508, 4-2-3-fluoro-4-trifluoromethyl phenyl-4-methyl-1,3-thiazol-5-yl methyl sulfanyl-2-methylphenoxy acetic acid, 4-2-3-fluoro-4-trifluoromethyl-phenyl-4-methyl-thiazol-5-ylmethylsulfanyl-2-methyl-phenoxy-acetic acid, 3tkm, 4-2-3-fluoro-4-trifluoromethyl phenyl-4-methyl-1,3-thiazol-5-yl methyl sulfanyl-2-methylphenoxyacetic acid, gwdelta 0742, d0k1tq, dsstox_cid_20760, dsstox_rid_79591, dsstox_gsid_40760
9934458
CHEBI:79991
2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid
CC1=C(C=CC(=C1)SCC2=C(N=C(S2)C3=CC(=C(C=C3)C(F)(F)F)F)C)OCC(=O)O
This item is not returnable. View return policy
317318-84-6
C21H17F4NO3S2
471.485
HWVNEWGKWRGSRK-UHFFFAOYSA-N
chembl38508, 4-2-3-fluoro-4-trifluoromethyl phenyl-4-methyl-1,3-thiazol-5-yl methyl sulfanyl-2-methylphenoxy acetic acid, 4-2-3-fluoro-4-trifluoromethyl-phenyl-4-methyl-thiazol-5-ylmethylsulfanyl-2-methyl-phenoxy-acetic acid, 3tkm, 4-2-3-fluoro-4-trifluoromethyl phenyl-4-methyl-1,3-thiazol-5-yl methyl sulfanyl-2-methylphenoxyacetic acid, gwdelta 0742, d0k1tq, dsstox_cid_20760, dsstox_rid_79591, dsstox_gsid_40760
9934458
CHEBI:79991
2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid
CC1=C(C=CC(=C1)SCC2=C(N=C(S2)C3=CC(=C(C=C3)C(F)(F)F)F)C)OCC(=O)O

Description

Highly selective, potent PPARδ agonist

Potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.
Quantity 10 mg
Formula Weight 471.49
Percent Purity >98%
Chemical Name or Material GW 0742

Safety and Handling

Recommended Storage Desiccate at +4°C
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