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Tocris Bioscience™ GW 0742
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Catalog No. 222910
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Catalog No. Quantity
22-291-0 10 mg
22-295-0 50 mg
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Catalog No. 22-291-0 Supplier Tocris Bioscience™ Supplier No. 2229/10
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Description

Highly selective, potent PPARδ agonist

Potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.

Chemical Identifiers

CAS 317318-84-6
Molecular Formula C21H17F4NO3S2

Specifications

Quantity 10 mg
Formula Weight 471.49
Purity >98%
Molecular Weight (g/mol) 471.485
Chemical Name or Material GW 0742

Safety and Handling

Recommended Storage Desiccate at +4°C
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