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Tocris Bioscience™ GW 2580 Available on GSA/VA Contract for Federal Government customers only.

Selective cFMS kinase inhibitor; orally bioavailable

$146.10 - $612.00

Specifications

Chemical Name or Material 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Molecular Formula C20H22N4O3
CAS 870483-87-7
Product Type Target: Additional RTK Inhibitors
Formula Weight 366.41
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
56-731-0 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5673/10
10mg Each for $146.10
Add to cart
 
56-735-0 View Documents Tocris Bioscience™
5673/50
50mg Each for $612.00
Add to cart
 
Description

Description

Potent and selective cFMS kinase inhibitor (IC50 = 0.06 μM). Exhibits selectivity for cFMS kinase over 186 other kinases. Inhibits CSF-1-induced growth of rat monocytes in vitro. Also inhibits bone resorption in osteoclast cultures, as well as connective tissue and bone destruction in a rat adjuvant arthritis model. Suppresses M-NFS-60 tumor cell growth in mice. Orally bioavailable.

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Specifications

Specifications

5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
870483-87-7
366.41
C20H22N4O3
Target: Additional RTK Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at −20°C

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