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  5. Tocris Bioscience™ GW 3965 hydrochloride

Tocris Bioscience™ GW 3965 hydrochloride
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Catalog No. 247410
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Orally active liver X receptor (LXR) agonist

Selective, orally active non-steroidal agonist for the liver X receptor (LXR). In cell-based reporter gene assays, acts as a full agonist of hLXRα and hLXRβ (EC50 values are 190 and 30 nM respectively). Reduces angiotensin II-mediated increases in blood pressure; up-regulates ABCA1 gene expression and raises circulating HDL levels. Displays potent antiatherogenic activity in mouse models of atherosclerosis.

Chemical Identifiers

CAS 405911-17-3
Molecular Formula C33H32Cl2F3NO3

Specifications

Quantity 10 mg
Formula Weight 618.51
Purity >98%
Molecular Weight (g/mol) 618.518
Chemical Name or Material GW 3965 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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