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Tocris Bioscience™ H 1152 dihydrochloride
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Catalog No. 24141
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24-141 1 mg
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Catalog No. 24-141 Supplier Tocris Bioscience™ Supplier No. 2414/1
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Description

Selective Rho-kinase (ROCK) inhibitor

Rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 μM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats.

Glycyl Derivative also available.

Chemical Identifiers

CAS 871543-07-6
Molecular Formula C16H23Cl2N3O2S

Specifications

Quantity 1 mg
Formula Weight 392.34
Purity >98%
Molecular Weight (g/mol) 392.339
Chemical Name or Material H 1152 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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