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HACE1 Monoclonal Antibody (OTI4E10), TrueMAB™, OriGene
SDP

Catalog No. p-200015699
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100 μL
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Catalog No. Quantity
50-168-3171 100 μL
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Catalog No. 50-168-3171 Supplier OriGene Supplier No. TA810060
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Description

Mouse Monoclonal Antibody

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

Specifications

Antigen HACE1
Applications Western Blot
Classification Monoclonal
Clone OTI4E10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene HACE1
Gene Accession No. Q8IYU2
Gene Alias SPPRS
Gene Symbols HACE1
Host Species Mouse
Immunogen Full length human recombit protein of human HACE1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57531
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2c
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