HAVCR2 Mouse anti-Human, Clone:7C8A7, Abnova™

Catalog No.	Quantity
89-333-956	100 μg

Catalog No. 89-333-956 Supplier Abnova Corporation Supplier No. MAB17617

Description

Mouse monoclonal antibody raised against recombinant human HAVCR2.

CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM]

Specifications

• Antigen: HAVCR2
• Applications: ELISA, Flow Cytometry, Immunocytochemistry
• Classification: Monoclonal
• Clone: 7C8A7
• Conjugate: Unconjugated
• Description: hepatitis A virus cellular receptor 2
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunocytochemistry (1:200-1:1000)
  Flow Cytometry (1:200-1:400)
  Immunohistochemistry
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: HAVCR2
• Gene Alias: FLJ14428, KIM-3, TIM3, TIMD3, Tim-3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 22-202 of human HAVCR2 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 84868
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1