Invitrogen™ HBS1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556241

Catalog No. PIPA556241

Description

Immunogen sequence: RNVRGYNYDE DFEDDDLYGQ SVEDDYCISP STAAQFIYSR RDKPSVEPVE EYDYEDLKES SNSVSNHQLS GFDQARLYSC LDHMREVLGD AVPDEI Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 88%.

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Specifications

• Antigen: HBS1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HBS1L
• Gene Alias: 2810035F15Rik; AI326327; EF-1a; eRF3 family member; eRF3c; ERF3-similar protein; ERFS; eukaryotic release factor 3; Hbs1; HBS1 like translational GTPase; HBS1L; Hbs1-like (S. cerevisiae); HBS1-like protein; HBS1-like translational GTPase; Hsp70 subfamily B suppressor 1-like protein; HSPC276; Kiaa1038
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10767
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y450
• Gene Symbols: HBS1L
• Immunogen: Recombinant protein corresponding to Human HBS1L. Recombinant protein control fragment (Product #RP-94690).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG