HECT E3 ubiquitin ligase inhibitor
Manufacturer: Tocris 5433/50
DescriptionHECT E3 ubiquitin ligase inhibitor; inhibits Nedd4, Smurf2 and WWP1 (IC50 values are 6.3, 6.8 and 6.9µM respectively). Selective for HECT-mediated over RING-mediated ubiquitination.
- Chemical Name: N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide
- Formula: C17H17NO3
- CAS Number: 890605-54-6
- Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
- Purity: >98
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