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Tocris™ Heclin

HECT E3 ubiquitin ligase inhibitor

Manufacturer:  Tocris™ 5433/50

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Catalog No. 54-335-0

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For Research Use Only



HECT E3 ubiquitin ligase inhibitor; inhibits Nedd4, Smurf2 and WWP1 (IC50 values are 6.3, 6.8 and 6.9µM respectively). Selective for HECT-mediated over RING-mediated ubiquitination.
  • Chemical Name: N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide
  • Formula: C17H17NO3
  • CAS Number: 890605-54-6
  • Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
  • Purity: >98
Description & Specifications


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