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Invitrogen™ Histone H1.2 Recombinant Superclonal™ Antibody (3HCLC)

Catalog No. 711909
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71-190-9 100 μg
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Catalog No. 71-190-9 Supplier Invitrogen™ Supplier No. 711909
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Description

Rabbit Recombinant Superclonal Antibody

This antibody is predicted to react with Monkey, Pig, Bovine. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called 'Recombinant polyclonal antibody', this product is now rebranded as 'Recombinant Superclonal™ antibody'. The physical product and the performance remain unchanged.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Histone H1.2
Applications ChIP Assay, Immunocytochemistry
Classification Recombinant Superclonal
Clone 3HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene H1-2
Gene Accession No. P16403
Gene Alias 0610008C09Rik; CTL-1; H1 histone family, member 2; H1 VAR.1; H1.2; H1.2 linker histone, cluster member; H1-2; H1C; H1f2; H1s-1; H1var1; His1a; Hist1h1c; histone 1, H1c; histone cluster 1, H1c; histone H1; histone H1.1; histone H1.2; Histone H1c; histone H1d; Histone H1s-1; LOC684681; MGC3992; similar to Histone H1.2 (H1 VAR.1) (H1c)
Gene Symbols H1-2, HIST1H1C
Host Species Rabbit
Immunogen Peptides corresponding to human Histone H1.2 [1) aa115-aa129 2) aa21-aa35].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3006
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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