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HIV-1 Gag p24 Antibody (HIV1-24/661), DyLight 550, Novus Biologicals™
SDP

Catalog No. NBP234636R Shop All R&D Systems Products
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Catalog No. NBP234636R Supplier Novus Biologicals Supplier No. NBP234636R
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Description

Mouse Monoclonal Antibody

HIV-1 Gag p24 Monoclonal antibody specifically detects HIV-1 Gag p24 in Virus samples. It is validated for ELISA, Immunocytochemistry, Immunofluorescence.

Specifications

Antigen HIV-1 Gag p24
Applications ELISA, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone HIV1-24/661
Conjugate DyLight 550
Dilution ELISA, Immunocytochemistry/Immunofluorescence
Gene Accession No. P04585, P04585
Gene Alias Capsid protein p24, Human immunodeficiency virus 1, Human immunodeficiency virus type 1 p24
Gene Symbols gag
Host Species Mouse
Immunogen Recombinant HIV-1 Gag p24 protein (Uniprot: P04585)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 155030
Test Specificity Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.
Target Species Virus
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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