HLA DQ/DR/DP Antibody (CR3/43), Alexa Fluor™ 532, Novus Biologicals™

Catalog No.	Quantity
NP2407A32	0.1 mL

Catalog No. NP2407A32 Supplier Novus Biologicals Supplier No. NBP254507AF532

Description

Mouse Monoclonal Antibody

HLA DPB1 Monoclonal specifically detects HLA DPB1 in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: HLA DPB1
• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: CR3/43
• Conjugate: Alexa Fluor 532
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Alias: DP beta 1 chain, DPB1, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA DP14-beta chain, HLA-DP histocompatibility type, beta-1 subunit, HLA-DP1B, HLA-DPB, major histocompatibility complex class II HLA DPB1 protein, major histocompatibility complex, class II, DP beta 1, MHC class II antigen beta chain, MHC class II antigen DP beta 1 chain, MHC class II antigen DPB1, MHC class II antigen DPbeta1, MHC class II HLA-DP-beta, MHC HLA DPB1
• Gene Symbols: HLA-DPB1
• Host Species: Mouse
• Immunogen: Cells from human tonsil
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Gene ID (Entrez): 3115
• Test Specificity: Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
• Target Species: Human
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG1 κ