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HLA DR/DP Antibody (Bra-14), PE/Cy5.5, Novus Biologicals™
SDP

Catalog No. N24806PECY5 Shop All R&D Systems Products
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N24806PECY5 0.1 mL
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Catalog No. N24806PECY5 Supplier Novus Biologicals Supplier No. NBP248006PECY55
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Description

Mouse Monoclonal Antibody

HLA DR/DP Monoclonal specifically detects HLA DR/DP in Human samples. It is validated for Flow Cytometry.

Specifications

Antigen HLA DR/DP
Applications Flow Cytometry
Classification Monoclonal
Clone Bra-14
Conjugate PE-Cyanine5.5
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Gene Symbols HLA-DRA
Host Species Mouse
Immunogen Human REH cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 3122.0
Test Specificity Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Target Species Human
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG3 κ
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