HLA DRA Antibody (169-1B5.2), Alexa Fluor™ 532, Novus Biologicals™

Catalog No.	Quantity
NP247722A32	0.1 mL

Catalog No. NP247722A32 Supplier Novus Biologicals Supplier No. NBP247722AF532

Description

Mouse Monoclonal Antibody

HLA DRA Monoclonal specifically detects HLA DRA in Human, Bovine, Feline samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

• Antigen: HLA DRA
• Applications: Flow Cytometry, Immunofluorescence
• Classification: Monoclonal
• Clone: 169-1B5.2
• Conjugate: Alexa Fluor 532
• Dilution: Flow Cytometry, Immunofluorescence
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Alias: FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
• Gene Symbols: HLA-DRA
• Host Species: Mouse
• Immunogen: Human peripheral blood leukocytes (Uniprot: P01903)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Gene ID (Entrez): 3122
• Test Specificity: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
• Target Species: Human, Bovine, Feline
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG2b κ