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  6. HLA DRA Antibody (169-1B5.2) - Azide and BSA Free, Novus Biologicals™

HLA DRA Antibody (169-1B5.2) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP247722B Shop All R&D Systems Products
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0.2 mg
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Catalog No. Quantity
NBP247722B 0.2 mg
NBP247722A 0.1 mg
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Catalog No. NBP247722B Supplier Novus Biologicals Supplier No. NBP2477220.2MG

Description

Mouse Monoclonal Antibody

HLA DRA Monoclonal antibody specifically detects Antigen in Bovine, Feline, Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen HLA DRA
Applications Flow Cytometry, Immunofluorescence, CyTOF
Classification Monoclonal
Clone 169-1B5.2
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Gene Symbols HLA-DRA
Host Species Mouse
Immunogen Human peripheral blood leukocytes
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 3122
Test Specificity This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Target Species Human, Bovine, Feline
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2b κ
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