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HLA DRA Antibody (19-26.1 (same as MB-26.1)) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248106 Shop All R&D Systems Products
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NBP248106 7 mL
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Catalog No. NBP248106 Supplier Novus Biologicals Supplier No. NBP248106
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Description

Mouse Monoclonal Antibody

HLA DRA Monoclonal specifically detects HLA DRA in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen HLA DRA
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 19-26.1 (same as MB-26.1)
Conjugate Unconjugated
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Gene Symbols HLA-DRA
Host Species Mouse
Immunogen Raji Cells
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Adaptive Immunity, Cell Biology, Diabetes Research, Immunology
Primary or Secondary Primary
Gene ID (Entrez) 3122
Test Specificity This monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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