HLA DRB1 Antibody (LN-3 + HLA-DRB/1067), PerCP, Novus Biologicals™

Catalog No.	Quantity
NB247672PCP	0.1 mL

Catalog No. NB247672PCP Supplier Novus Biologicals Supplier No. NBP247672PCP

Description

Mouse Monoclonal Antibody

HLA DRB1 Monoclonal specifically detects HLA DRB1 in Human, Monkey samples. It is validated for Flow Cytometry.

Specifications

• Antigen: HLA DRB1
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: LN-3 + HLA-DRB/1067
• Conjugate: PerCP
• Dilution: Flow Cytometry
• Formulation: PBS with 0.05% Sodium Azide
• Gene Alias: Clone P2-beta-3, DR1, DR-1, DR12, DR-12, DR13, DR-13, DR14, DR-14, DR16, DR-16, DR4, DR-4, DR5, DR-5, DR7, DR-7, DR8, DR-8, DR9, DR-9, DRB1, DRw10, DRw11, DRw8, DW2.2/DR2.2, FLJ75017, FLJ76359, HLA class II antigen beta chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA-DR1B, HLA-DRB, HLA-DRB1*, HLA-DRB2, HLA-DR-beta 1, human leucocyte antigen DRB1, leucocyte antigen DR beta 1 chain, leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen DRB1*1, MHC class II antigen DRB1*10, MHC class II antigen DRB1*11, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*4, MHC class II antigen DRB1*7, MHC class II antigen DRB1*8, MHC class II antigen DRB1*9, MHC class II antigen HLA-DR13, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface gly
• Gene Symbols: HLA-DRB1
• Host Species: Mouse
• Immunogen: Activated human peripheral blood mononuclear cells (LN-3 and HLA-DRB/1067)
• Purification Method: Protein A or G purified
• Quantity: 0.1 mL
• Research Discipline: Adaptive Immunity, Asthma, Cell Biology, Diabetes Research, Immunology
• Primary or Secondary: Primary
• Gene ID (Entrez): 3123
• Test Specificity: This monoclonal antibody reacts with the beta-chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
• Target Species: Human, Monkey
• Content And Storage: Store at 4C in the dark.
• Form: Purified
• Isotype: IgG2b κ