HNF1B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-8046	Proteintech Group Inc 125331AP150UL	150 μL

Description

This is a rabbit polyclonal antibody raised against the N-terminal region of human HNF1B. HNF1B exists some isoforms with MW of 61 kDa, 58 kDa, 46 kDa, and 44 kDa.

Hepatocyte Nuclear Factor 1 (HNF1, Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor) is a member of the homeodomain-containing superfamily of transcription factors. It is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. HNF1has been shown to function in nephron development and regulates development of the embryonic pancreas. Mutations in the gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of the gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: HNF1B
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P23899, P27889, P35680
• Gene ID (Entrez): 21410, 25640, 6928
• Immunogen: HNF1B Fusion Protein Ag3232
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: HNF1B

• Concentration: 0.28 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: FJHN, HNF 1 beta, HNF 1B, HNF1 homeobox B, HNF1B, HNF1beta, HNF2, Homeoprotein LFB3, HPC11, LF B3, LFB3, MODY5, TCF 2, TCF2, Transcription factor 2, VHNF1
• Gene Symbols: Hnf1b
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody