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HSP27 Antibody (G3.1), PerCP, Novus Biologicals™
SDP

Catalog No. NBP234621P Shop All R&D Systems Products
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NBP234621P 0.1 mL
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Catalog No. NBP234621P Supplier Novus Biologicals Supplier No. NBP234621PCP
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Description

Mouse Monoclonal Antibody

HSP27 Monoclonal specifically detects HSP27 in Human, Mouse, Rat, Chicken, Chimpanzee, Monkey, Sheep samples. It is validated for Flow Cytometry.

Specifications

Antigen HSP27
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone G3.1
Conjugate PerCP
Dilution Flow Cytometry
Gene Alias 28 kDa heat shock protein, DKFZp586P1322, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, heat shock 27kD protein 1, heat shock 27kDa protein 1, heat shock protein beta-1, HMN2B, HS.76067, Hsp25, HSP27HSP 27, HSP28CMT2F, HspB1, SRP27, Stress-responsive protein 27
Gene Symbols HSPB1
Host Species Mouse
Immunogen Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.
Molecular Weight of Antigen 27 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cell Cycle and Replication, Golgi Apparatus Markers, Membrane Trafficking and Chaperones, Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) 3315
Test Specificity monoclonal antibody G3.1 reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian alpha-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors.
Target Species Human, Mouse, Rat, Chicken, Primate, Sheep
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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