HSP27 Mouse, Clone: SPM252, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2328650.2MG
DescriptionHSP27 Monoclonal antibody specifically detects Antigen in Chicken, Human, Mouse, Primate, Rat, Sheep samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Paraffin), Western Blotting.
|Western Blot 0.25-0.5ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml|
|28 kDa heat shock protein, DKFZp586P1322, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, heat shock 27kD protein 1, heat shock 27kDa protein 1, heat shock protein beta-1, HMN2B, HS.76067, Hsp25, HSP27HSP 27, HSP28CMT2F, HspB1, SRP27, Stress-responsive protein 27|
|Protein A purified|
|Store at 4C.|
|It recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced p29 and 24K protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.|
|Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|PBS with 0.05% BSA. with 0.05% Sodium Azide|
|Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.|
|Cancer, Cell Biology, Cell Cycle and Replication, Golgi Apparatus Markers, Membrane Trafficking and Chaperones, Neuroscience, Phospho Specific|
|Human, Mouse, Rat, Chicken, Primate, Sheep|
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