Human Neuregulin-1/NRG1 Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 9 publications

Catalog Number	Mfr. No.	Quantity
MAB377SP	R&D Systems MAB377SP	25 μg
MAB377100	R&D Systems MAB377100	100 μg
MAB377500	R&D Systems MAB377500	500 μg

Description

Neuregulin-1/NRG1 Monoclonal specifically detects Neuregulin-1/NRG1 in Human samples. It is validated for Western Blot.

Specifications

• Antigen: Neuregulin-1/NRG1
• Dilution: Western Blot 1 ug/mL
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: AAA58639
• Gene ID (Entrez): 3084
• Immunogen: E. coli-derived recombinant human Neuregulin-1/NRG1 Ser2-Lys246 Accession # AAA58639
• Primary or Secondary: Primary
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Test Specificity: Detects human Neuregulin-1/NRG1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with the EGF-like domains of recombinant human (rh) NRG1-beta 1 (aa 176-246) or rhNRG1-alpha (aa 177-241). Therefore, this antibody recognizes an epitope located within aa 2-176 segment N-terminal to the EGF-like domain. This segment is present in all NRG1-alpha , beta and gamma isoforms and in NDF43 and glial growth factor (GGF). It is absent from the NRG1 gene products GGF2 and SMDF.

• Clone: 147724
• Applications: Western Blot
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
• Gene Alias: ARIA, GGF2, GGFglial growth factor, Heregulin-1, HGL, HGLneu differentiation factor, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGAneuregulin 1 type IV beta 1a, MST131, MSTP131, NDFheregulin, alpha (45kD, ERBB2 p185-activator), neuregulin 1, neuregulin 1 type IV beta 3, Neuregulin1, NRG1, pro-neuregulin-1, membrane-bound isoform, pro-NRG1, sensory and motor neuron derived factor, SMDF
• Gene Symbols: NRG1
• Isotype: IgG2b
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.