Invitrogen™ HUNK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532872

Catalog No. PIPA532872

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Bovine, Elephant (100%); Rabbit (95%); Gibbon, Marmoset, Dog, Panda, Horse (89%); Mouse, Rat, Hamster (84%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

HUNK serine/threonine kinase or hormonally up-regulated Neu-associated kinase is a member of the mitogen-activated protein kinase family which is essential for mammary tumor metastasis. HUNK deletion in mice did not alter viability, fertility, longevity, or propensity to develop tumors and it is also dispensable for murine development. HUNK has been shown to participate in vesicular transport. Additionally, functional studies in mice suggest that HUNK regulates endocytosis via interaction with rabaptin-5 protein and induces changes in mammary glands during pregnancy. HUNK expression has been documented in mouse brain, breast, embryo, and fetus. ESTs have been isolated from several human tissue libraries, including normal ear.

Specifications

• Antigen: HUNK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HUNK
• Gene Alias: B19; Bstk1; Hormonally up-regulated neu tumor-associated kinase; hormonally upregulated neu tumor-associated kinase; hormonally up-regulated Neu-associated kinase; hormonally upregulated Neu-associated kinase; Hunk; MAKV; Mak-v; RGD1565091; serine/threonine protein kinase MAK-V; serine/threonine-protein kinase MAK-V
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30811, 537640
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P57058
• Gene Symbols: HUNK
• Immunogen: Synthetic 19 amino acid peptide from C-terminal cytoplasmic domain of human HUNK.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Bovine
• Product Type: Antibody
• Isotype: IgG