Thermo Scientific™ Hypersil™ Chiral HPLC Columns

Catalog No.	Length (Metric)	Diameter (Metric)	Particle Size	Stationary Phase
03-253-761	100 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-746	50 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-747	100 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-748	150 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-749	250 mm	4.6 mm	3 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-750	100 mm	4.6 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-751	150 mm	4.6 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-752	250 mm	4.6 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-756	250 mm	10 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-757	250 mm	20 mm	5 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-753	100 mm	4.6 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-754	150 mm	4.6 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-755	250 mm	4.6 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-758	250 mm	10 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-759	250 mm	20 mm	10 μm	Cellulose-tris-(3,5-dimethylphenyl-carbamate)
03-253-760	50 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-762	150 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-763	250 mm	4.6 mm	3 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-764	100 mm	4.6 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-765	150 mm	4.6 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-766	250 mm	4.6 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-770	250 mm	10 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-771	250 mm	20 mm	5 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-767	100 mm	4.6 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-768	150 mm	4.6 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-769	250 mm	4.6 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-772	250 mm	10 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-773	250 mm	20 mm	10 μm	Amylose-tris-(3,5-dimethylphenyl-carbamate)
03-253-774	100 mm	4.6 mm	3 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-775	150 mm	4.6 mm	3 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-776	250 mm	4.6 mm	3 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-777	100 mm	4.6 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-778	150 mm	4.6 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-779	250 mm	4.6 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-783	250 mm	10 mm	5 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-780	100 mm	4.6 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-781	150 mm	4.6 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-782	250 mm	4.6 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose
03-253-784	250 mm	10 mm	10 μm	Tris-(4-Methylbenzoyl)-Cellulose

Catalog No. 03-253-761 Supplier Thermo Scientific™ Supplier No. 42103104630

Description

Resolve enantiomers with Hypersil Chiral HPLC columns in normal phase mode for confident purification of your target compound.

Separate a wide range of enantiomers with Thermo Scientific™ Hypersil™ Chiral HPLC columns, designed for separations of neutral, acidic and basic racemates in normal phase. These chiral columns can help ensure your purification needs are met by resolving racemic mixtures and potential contaminants so you can be confident in the purity of your target compound. To maximize screening efficiency, these columns can be ordered in kits which contain a column in each of our chiral phases. All columns are available in analytical and preparative scale formats.

Separate Enantiomers

Hypersil Chiral JT

• Best starting point for method development.
• Chemistry: Tris-(4-methylbenzoyl)-cellulose modified silica.
• USP L80.

Hypersil Chiral AT

• Highest generality of all chiral phases.
• No aromatic ring necessary.
• No inversion of elution order possible.
• Chemistry: Amylose tris-3,5-dimethylphenylcarbamate modified silica.
• USP L51.

Hypersil Chiral OT

• Highly versatile chiral phases.
• No aromatic ring necessary.
• No inversion of elution order possible.
• Chemistry: Cellulose tris-(3.5-dimethylphenyl-carbamate) modified silica.
• USP L40.

Chiral Column Kits

• Contain three columns, one of each Hypersil Chiral JT, Hypersil Chiral AT, and Hypersil Chiral OT.

HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

• Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
• Standard threaded hardware for column i.d. < 40mm.
• Standard flange hardware for column i.d. ≥ 40mm.
• Standard hardware can be modified on request to be compatible with SFC.

Customer Specific Orders

• There are many other Chiral Stationary Phases (CSP’S) available from Thermo Scientific including immobilized brush-type phases. If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in preparative scale or would like to discuss a specific phase that is not listed above, we would be happy to discuss your requirements.
• Please contact your local sales representative for Customer Specific Orders.
• Custom built columns are not eligible for returns.

Specifications

• Column Format: Preparative Column and Analytical Column, Standard
• Diameter (Metric): 4.6 mm
• Length (Metric): 100 mm
• Max. Pressure: 3700 psi (255 bar)
• Particle Size: 3 μm
• Pore Size: 1000 Å
• Surface Area: 30 m²/g
• Temperature: Room Temperature
• USP Type: L51
• Stationary Phase: Amylose-tris-(3,5-dimethylphenyl-carbamate)
• Packing Material: Spherical, Fully Porous Silica
• Column Type: Chiral Separation
• Endcapped: No
• Phase: Chiral Separation