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Thermo Scientific™ Hypersil™ PREP Si HPLC Columns
Description
Separate nonpolar and moderately polar organic compounds with Hypersil PREP Si prep LC columns for normal phase methods, suitable for USP L3 applications.
Use Thermo Scientific™ Hypersil™ PREP Si preparative HPLC columns to scale up your normal phase chromatography analytical method. The silica chemistry separates nonpolar and moderately polar organic compounds. Our preparative HPLC columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.
Normal phase chromatography
- Silica to separate nonpolar and moderately polar organic compounds.
- USP L3.
- pH stable from 2 to 7.
- Maximum temperature of 60°C.
Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.
Standard Threaded and Standard Flange Hardware
- Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
- Standard threaded hardware for column i.d. < 40mm.
- Standard flange hardware for column i.d. ≥ 40mm.
- Standard hardware can be modified on request to be compatible with SFC.
XtendedLife Hardware
- Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
- Compatible with SFC and is available in dimensions up to 50mm i.d.
Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.
Customer Specific Orders
- If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
- Please contact your local sales representative for Customer Specific Orders.
- Custom built columns are not eligible for returns.

Specifications
Specifications
Column Format | Preparative Column, Standard |
Diameter (Metric) | 30 mm |
Length (Metric) | 150 mm |
Max. Pressure | 2200 psi (152 bar) |
Particle Size | 5 μm |
pH | 2 to 7 |
Pore Size | 130 Å |
Surface Area | 195 m²/g |
Temperature | 60°C |
USP Type | L3 |
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