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Tocris Bioscience™ ICA 121431
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Catalog No. 506610
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective NaV1.3 and NaV1.1 channel blocker

Potent and selective inhibitor of human NaV1.3 and NaV1.1 channels (IC50 values are 13 and 23 nM respectively). Exhibits up to 1,000 fold selectivity against other TTX-sensitive or resistant sodium channels (IC50 values are >10 μM for human NaV1.5 and NaV1.8 channels). Interacts with an inhibitory interaction site distinct from those bound by TTX and local anesthetic-like modulators.

Chemical Identifiers

CAS 313254-51-2
Molecular Formula C23H19N3O3S2

Specifications

Quantity 10 mg
Formula Weight 449.55
Physical Form Solid
Color White
Purity >98%
Molecular Weight (g/mol) 449.543
Chemical Name or Material ICA 121431

Safety and Handling

Recommended Storage Store at +4°C
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