Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Diphenylmethanes
  8. ICA 121431, Tocris Bioscience™ 

ICA 121431, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

Click to view available options
Quantity:
10mg
50mg
This item is not returnable. View return policy
313254-51-2
C23H19N3O3S2
449.543
URSQNPPONHUJDL-UHFFFAOYSA-N
2,2-diphenyl-n-4-n-thiazol-2-yl sulfamoyl phenyl acetamide, 2,2-diphenyl-n-4-1,3-thiazol-2-ylsulfamoyl phenyl acetamide, 2,2-diphenyl-n-4-thiazol-2-ylsulfamoyl-phenyl-acetamide, 2,2-diphenyl-n-4-1,3-thiazol-2-yl sulfamoyl phenyl acetamide, 2,2-diphenyl-n-4-1,3-thiazol-2-ylamino sulfonyl phenyl acetamide, alpha-phenyl-n-4-2-thiazolylamino sulfonyl phenyl-benzeneacetamide
998021
2,2-diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)NC4=NC=CS4
This item is not returnable. View return policy
313254-51-2
C23H19N3O3S2
449.543
URSQNPPONHUJDL-UHFFFAOYSA-N
2,2-diphenyl-n-4-n-thiazol-2-yl sulfamoyl phenyl acetamide, 2,2-diphenyl-n-4-1,3-thiazol-2-ylsulfamoyl phenyl acetamide, 2,2-diphenyl-n-4-thiazol-2-ylsulfamoyl-phenyl-acetamide, 2,2-diphenyl-n-4-1,3-thiazol-2-yl sulfamoyl phenyl acetamide, 2,2-diphenyl-n-4-1,3-thiazol-2-ylamino sulfonyl phenyl acetamide, alpha-phenyl-n-4-2-thiazolylamino sulfonyl phenyl-benzeneacetamide
998021
2,2-diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)NC4=NC=CS4

Description

Potent and selective NaV1.3 and NaV1.1 channel blocker

Potent and selective inhibitor of human NaV1.3 and NaV1.1 channels (IC50 values are 13 and 23 nM respectively). Exhibits up to 1,000 fold selectivity against other TTX-sensitive or resistant sodium channels (IC50 values are >10 μM for human NaV1.5 and NaV1.8 channels). Interacts with an inhibitory interaction site distinct from those bound by TTX and local anesthetic-like modulators.

This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.

Quantity 10mg
Color White
Formula Weight 449.55
Physical Form Solid
Percent Purity >98%
Chemical Name or Material ICA 121431

Safety and Handling

Recommended Storage : Store at +4°C