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IDH2 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA582315
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100 μL
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Catalog No. Quantity
PIPA582315 100 μL
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Catalog No. PIPA582315 Supplier Thermo Scientific Supplier No. PA582315

Description

Rabbit Polyclonal Antibody

Immunogen sequence: REPIICKNIP RLVPGWTKPI TIGRHAHGDQ YKATDFVADR AGTFKMVFTP KDGSGVKEWE VYNFPAGGVG MGMYNTDESI SGFAHSCFQY AIQKKWPLYM STKNTILKAY DGRFKDIFQE IFDKHYKTDF D

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NADas the electron acceptor and the other NADP. Five isocitrate dehydrogenases have been reported: three NAD-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predomitly cytosolic. Each NADP-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IDH2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IDH2
Gene Accession No. P48735, P56574, P54071
Gene Symbols IDH2
Host Species Rabbit
Immunogen Recombit protein corresponding to Human IDH2
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 269951, 3418, 361596
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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