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  6. IFN-alpha 2 Antibody (N39) - Azide and BSA Free, Novus Biologicals™

IFN-alpha 2 Antibody (N39) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NB254398200 Shop All R&D Systems Products
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NB254398200 200 μg
NB254398100 100 μg
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Catalog No. NB254398200 Supplier Novus Biologicals Supplier No. NBP254398200UG

Description

Mouse Monoclonal Antibody

IFN-alpha 2 Monoclonal antibody specifically detects IFN-alpha 2 in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, CyTOF-ready.

Specifications

Antigen IFN-alpha 2
Applications Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, CyTOF
Classification Monoclonal
Clone N39
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells, ELISA 1:100 - 1:2000, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias alpha-2a interferon, IFNA, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765
Gene Symbols IFNA2
Host Species Mouse
Immunogen Purified recombinant human IFN-alpha2
Molecular Weight of Antigen 22 kDa
Purification Method Protein A or G purified
Quantity 200 μg
Regulatory Status RUO
Research Discipline Biologically Active Proteins
Primary or Secondary Primary
Gene ID (Entrez) 3440
Test Specificity Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
Target Species Human
Content And Storage Store at -20 to -80C. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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