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IgA (α-Heavy Chain) Ab-2 Rabbit Polyclonal Antibody, Epredia™

Catalog No. p-4548978 Shop All Epredia Products
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500 μL
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7 mL
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Catalog No. Quantity Form
RB1433A1 500 μL Concentrated
RB1433A0 100 μL Concentrated
RB1433A 1 mL Concentrated
RB1433R1 1 mL Prediluted
RB1433R7 7 mL Prediluted
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IgA (α-Heavy Chain) Ab-2, Rb PAb is one marker in a comprehensive ab portfolio that addresses all major disease states, ensuring the ideal tests are always available.

The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: IgA isolated from a pool of normal human sera

Molecular Weight: 50kDa

Positive Control: Tonsil

Cellular Localization: Cytoplasmic Ab-2 recognizes a protein of 50kDa, identified as alpha heavy chain of human immunoglobulins. It reacts with both IgA1 and IgA2 isotypes. Ab-2 does not cross-react with γ (IgG), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Ab-2 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen IgA (alpha-Heavy Chain) Ab-2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Host Species Rabbit
Immunogen IgA isolated from a pool of normal human sera
Quantity 500 μL
Regulatory Status IVD
Research Discipline Immunoglobulins
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG
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