IgA (α-Heavy Chain) Ab-2 Rabbit Polyclonal Antibody, Epredia™

IgA (α-Heavy Chain) Ab-2, Rb PAb is one marker in a comprehensive ab portfolio that addresses all major disease states, ensuring the ideal tests are always available.

Catalog Number	Mfr. No.	Quantity	Form
RB1433A1	Epredia RB1433A1	500 μL	Concentrated
RB1433A0	Epredia RB1433A0	100 μL	Concentrated
RB1433A	Epredia RB1433A	1 mL	Concentrated
RB1433R1	Epredia RB1433R1	1 mL	Prediluted
RB1433R7	Epredia RB1433R7	7 mL	Prediluted

Description

The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: IgA isolated from a pool of normal human sera

Molecular Weight: 50kDa

Positive Control: Tonsil

Cellular Localization: Cytoplasmic Ab-2 recognizes a protein of 50kDa, identified as alpha heavy chain of human immunoglobulins. It reacts with both IgA1 and IgA2 isotypes. Ab-2 does not cross-react with γ (IgG), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Ab-2 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: IgA (alpha-Heavy Chain) Ab-2
• Classification: Polyclonal
• Host Species: Rabbit
• Research Discipline: Immunoglobulins
• Immunogen: IgA isolated from a pool of normal human sera
• Primary or Secondary: Primary

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Regulatory Status: IVD
• Target Species: Human
• Isotype: IgG