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IGF-I/IGF-1 Antibody (IGF1/1020), Alexa Fluor™ 594, Novus Biologicals™
SDP

Catalog No. NP24801A594 Shop All R&D Systems Products
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NP24801A594 0.1 mL
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Catalog No. NP24801A594 Supplier Novus Biologicals Supplier No. NBP248001AF594
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Mouse Monoclonal Antibody

IGF-I/IGF-1 Monoclonal specifically detects IGF-I/IGF-1 in Human, Mouse, Rat, Rabbit samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

Antigen IGF-I/IGF-1
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone IGF1/1020
Conjugate Alexa Fluor 594
Dilution Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C
Gene Symbols IGF1
Host Species Mouse
Immunogen Recombinant full-length human IGF-I/IGF-1 protein (Uniprot: P05019)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Biologically Active Proteins, Cell Cycle and Replication, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 3479.0
Test Specificity This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Target Species Human, Mouse, Rat, Rabbit
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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