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IGF-I Mouse, Clone: M23, Novus Biologicals™
SDP

Catalog No. NBP234249A Shop All R&D Systems Products
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Catalog No. Quantity
NBP234249A 0.1 mg
NBP234249F 0.02 mg
NBP234249B 0.2 mg
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Catalog No. NBP234249A Supplier Novus Biologicals Supplier No. NBP2342490.1MG
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Description

Mouse Monoclonal Antibody

IGF-I/IGF-1 Monoclonal specifically detects IGF-I/IGF-1 in Human, Mouse, Rat, Rabbit samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen IGF-I
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone M23
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin 1-2ug/ml, SDS-Page
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P05019
Gene Alias IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C
Gene Symbols IGF1
Host Species Mouse
Immunogen Purified human IGF-1 protein
Molecular Weight of Antigen 7.6 kDa
Purification Method Protein A purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cell Cycle and Replication
Primary or Secondary Primary
Gene ID (Entrez) 3479
Test Specificity This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Target Species Human, Mouse, Rat, Rabbit
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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