IGF-I Mouse, Clone: M23, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP234249F	Novus Biologicals NBP2342490.02MG	0.02 mg
NBP234249A	Novus Biologicals NBP2342490.1MG	0.1 mg
NBP234249B	Novus Biologicals NBP2342490.2MG	0.2 mg

Description

IGF-I/IGF-1 Monoclonal specifically detects IGF-I/IGF-1 in Human, Mouse, Rat, Rabbit samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: IGF-I
• Dilution: Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin 1-2ug/ml, SDS-Page
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Mouse, Rat, Rabbit
• Gene Accession No.: P05019
• Gene ID (Entrez): 3479
• Immunogen: Purified human IGF-1 protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.
• Molecular Weight of Antigen: 7.6 kDa

• Clone: M23
• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Cell Cycle and Replication
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C
• Gene Symbols: IGF1
• Isotype: IgG1 κ
• Purification Method: Protein A purified
• Test Specificity: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.