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IGF1B Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 202151AP

Catalog No. 50-173-2772


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Description

Description

The antibody is specific to isoform IGF-1B.

Insulin-like growth factor-1 (IGF1), is structurally and functionally related to insulin but has a much higher growth-promoting activity. A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival. IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake. In circulation, IGFs are predomitly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues. Low levels of IGF1 have been linked to Alzheimer ft.s disease.
Specifications

Specifications

IGF1B
0.44 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P05019
IBP1, IGF I, IGF1, IGF1A, IGF1B, IGFI, Insulin like growth factor I, Mechano growth factor, MGF, Somatomedin C
Rabbit
IgG
150 μL
-20°C
Primary
3479
Immunohistochemistry (Paraffin)
Unconjugated
IGF1
Liquid
IGF1
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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