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Invitrogen™ IGF2BP3 Polyclonal Antibody
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Catalog No. PA549760
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100 μL
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PA549760 100 μL
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Catalog No. PA549760 Supplier Invitrogen™ Supplier No. PA549760
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total IGF2BP3 protein.

Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGF2BP3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IGF2BP3
Gene Accession No. O00425, Q9CPN8
Gene Alias 2610101N11Rik; AA522010; Ab2-255; AL022933; AU045931; cancer/testis antigen 98; CT98; hKOC; IGF2 mRNA-binding protein 3; IGF2BP3; IGF-II mRNA-binding protein 3; IMP3; IMP-3; insulin like growth factor 2 mRNA binding protein 3; insulin-l; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; insulin-like growth factor 2, binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC; KOC1; Koc13; mimp3; mIMP-3; Neilsen; RGD1306512; VICKZ family member 3; Vickz3
Gene Symbols IGF2BP3
Host Species Rabbit
Immunogen Synthesized peptide derived from N-terminal of human IGF2BP3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10643, 140488
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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