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IgG4 Mouse anti-Human, Clone: IGHG4/1345, Novus Biologicals™
SDP

Catalog No. NBP247639B Shop All R&D Systems Products
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0.2 mg
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NBP247639B 0.2 mg
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Catalog No. NBP247639B Supplier Novus Biologicals Supplier No. NBP2476390.2MG

Description

Mouse Monoclonal Antibody

IgG4 Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blotting.

Specifications

Antigen IgG4
Applications Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone IGHG4/1345
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunofluorescence 0.5-1ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols IGHG4
Host Species Mouse
Immunogen Recombinant human IGHG4 fragment
Molecular Weight of Antigen 150 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Reportedly, a large population of patients with recurrent respiratory tract infection has low IgG4 concentrations. IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis, and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells. IgG4 is overexpressed in inflammatory pseudotumor (IPT) and under expressed in inflammatory myofibroblastic tumo
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1
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