Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. NBP142423

IgY Antibody (7C2), Novus Biologicals™
SDP

Catalog No. NBP142423 Shop All R&D Systems Products
Change view
Click to view available options
Quantity:
0.05 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
NBP142423 0.05 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. NBP142423 Supplier Novus Biologicals Supplier No. NBP142423

Description

Mouse Monoclonal Antibody

IgY Monoclonal specifically detects IgY in Chicken samples. It is validated for Western Blot, Immunoprecipitation.

Specifications

Antigen IgY
Applications Western Blot, Immunoprecipitation
Classification Monoclonal
Clone 7C2
Conjugate Unconjugated
Dilution Western Blot 1:100-1:2000, Immunoprecipitation 1:10-1:500
Host Species Mouse
Immunogen The antibody reacts with the Chicken IgY antigen.
Purification Method Protein A or G purified
Quantity 0.05 mg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity The antibody can be used during various purification steps of IgY. The yolk of eggs laid by immunized chickens has been recognized as an excellent source of polyclonal antibodies (pAb). Specific antibodies produced in chickens offer several important advantages over producing antibodies in other mammals. Because a single egg contains as much antibody as an average bleed from a rabbit, this simple, non-invasive approach presents an appealing alternative to conventional pAb production methods. Purification of chicken egg yolk immunoglobulin Y (IgY), the 150 kDa IgG homolog, does not require animal bleeding. In addition, the eggs from immunized chickens provide a continual, daily source of pAb, and this convenient approach offers greater compatibility with animal protection regulations. Due to the phylogenetic distance between birds and mammals, there is greater potential of producing a higher percentage of specific antibody against mammalian antigens when using chickens. Highly conserved mammalian proteins sometimes fail to illicit a humoral response in animals, such as rabbits, that are traditionally used for generating pAb. Non-specific binding and need for cross-species immunoabsorptions is eliminated since chicken IgY does not cross-react with mammalian IgG and does not bind bacterial or mammalian Fc receptors. There are well defined structural differences of IgY-type immunoglobulins and the IgG of mammals.. That includes the molar mass of the heavy chains of the immunoglobulins. The IgY-type immunoglobulins are much less flexible than IgG. Also, the structures of the Fc part of the immunoglobulin isotypes IgY and IgG are different.
Target Species Chicken
Content And Storage Store at 4C. Do not freeze.
Form Purified
Isotype IgG1
Show More Show Less

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.