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IL-1 RI Antibody (JAMA-147), Alexa Fluor™ 405, Novus Biologicals™
SDP

Catalog No. NB10065865W Shop All R&D Systems Products
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NB10065865W 0.1 mL
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Catalog No. NB10065865W Supplier Novus Biologicals Supplier No. NB10065865AF405
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Description

Armenian Hamster Monoclonal Antibody

IL-1 RI Monoclonal specifically detects IL-1 RI in Mouse samples. It is validated for Block/Neutralize, Flow Cytometry, Immunoprecipitation.

Specifications

Antigen IL-1 RI
Applications Blocking Assay, Flow Cytometry, Immunoprecipitation
Classification Monoclonal
Clone JAMA-147
Conjugate Alexa Fluor 405
Dilution Flow Cytometry
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias CD121 antigen-like family member A, CD121a antigen, IL1R, IL1R1, IL1RT1, IL-1RT1, IL-1RT-1, Interleukin 1 Receptor 1, interleukin 1 receptor, type I, interleukin receptor 1, interleukin-1 receptor type 1, p80
Gene Symbols IL1R1
Host Species Armenian Hamster
Immunogen Extracellular domain of murine IL-1R.
Purification Method Protein G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cytokine Research, Immunology, Innate Immunity, Phospho Specific
Primary or Secondary Primary
Gene ID (Entrez) 3554
Test Specificity NB100-65865 recognizes murine CD121a, which is the 80kD type I interleukin-1 receptor. CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a. Clone JAMA-147 has been reported to block IL-1 dependent cellular responses. (1).
Target Species Mouse
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG
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For Research Use Only

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